公司名稱:南京康佰生物科技有限公司
地址:南京市雨花區長虹路222號
郵編:
電話:025-86880024
手機: 18066071954
聯系人: 蔣
傳真:
E-mail: zhangxiangwen@cobioer.com
地址:南京市雨花區長虹路222號
郵編:
電話:025-86880024
手機: 18066071954
聯系人: 蔣
傳真:
E-mail: zhangxiangwen@cobioer.com
CBP71347Human ADORA1/CHO的詳細資料:
CBP71347 | |
I. Background | |
ADORA1 is a receptor for adenosine. It is demonstrated that the ADORA1 receptor is ubiquitous throughout the entire body. Activation of ADORA1 elicits an inhibition of adenylate cyclase and therefore a decrease in the cAMP concentration. ADORA1 receptors are implicated in sleep promotion by inhibiting wake promoting cholinergic neurons in the basal forebrain. Adenosine antagonists are widely used in neonatal medicine. | |
II. Introduction | |
Host Cell: | CHO |
Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | F12k+10%FBS+5ug/ml puromycin |
Mycoplasma Status: | Negative |
Storage: | Liquid nitrogen immediately upon delivery |
Application(s): | Functional assay for A1 receptor |
Transducer: | Gq/Gi/Gs |
Ⅲ. Description of Host Cell Line | |
Organism: | Hamster |
Tissue: | Ovary |
Morphology: | Epithelial |
Growth Properties: | Adherent |
Ⅳ. Representative Data | |
Figure 1. NECA efffect on CHO-K1-ADORA1 clone 5. |